Setbacks and promises for drugs against Alzheimer's disease
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چکیده
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ADAGIO-Lipids gives promises but faces the setbacks.
The rapidly increasing global wave of obesity associated with cardiometabolic risk factors portends a daunting increase of cardiovascular disease. Consequently, the search for effective and safe drugs and new therapeutic avenues to fight obesity stands at the frontline because of a market with enormous opportunities. Rimonabant is a selective CB1 endocannabinoid receptor antagonist that was the...
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1. Dong H, Csernansky JG (2009) Effects of Stress and Stress Hormones on Amyloidβ Protein and Plaque Deposition. J Alzheimers Dis 18: 459-469. 2. Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, et al. (2006) Plasma cortisol and progression of dementia in subjects with Alzheimer‐ type dementia. Am J Psychiatry 163: 2164-2169. 3. Swaab DF, Raadsheer FC, Endert E, Hofman MA, Kamphorst W, et al. ...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2018
ISSN: 1469-221X,1469-3178
DOI: 10.15252/embr.201846714